Erythropoietin Bisosimilar
Erythropoietin, or its alternative erythropoetin or
EPO, is a glycoprotein hormone that controls erythropoiesis, or red
blood cell production. It is a cytokine for erythrocyte (red blood cell)
precursors in the bo
ne
marrow. Also called hematopoietin or hemopoietin, it is
produced by the peritubular capillary endothelial cells in the kidney,
and is the hormone that regulates red blood cell production. It also has
other known biological functions. For example, erythropoietin plays an
important role in the brain's response to neuronal injury.EPO is also
involved in the wound healing process.
When exogenous EPO is used as a performance-enhancing drug, it is classified as an erythropoiesis-stimulating agent (ESA). Exogenous EPO can often be detected in blood, due to slight difference from the endogenous protein, for example in features of posttranslational modification.